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If you choose to follow any links to the complete text of articles listed below, you will be leaving the Strategian Web site. If you wish to return to this page from the Web page you are sent to, please use the Back option of your browser. Gaetano Romano, Pietro Micheli, Carmen Pacilio, and Antonio Giordano Latest Developments in Gene Transfer Technology: Achievements, Perspectives, and Controversies over Therapeutic Applications. (... a review of the progress made, pitfalls encountered, and challenges to overcome in the development of the use of gene therapy to potentially treat a whole range of disorders including cancer, AIDS [HIV-1 infection], cardiovascular diseases, neurologic illnesses, and allergies as well as the use of gene transfer technology to develop innovative vaccines [genetic immunization]. Work on the use of genetic immunization in the development of an AIDS vaccine has already taken place, and use of this technique is being considered for developing vaccines against such disorders as malaria, tuberculosis, hepatitis A, B and C viruses, influenza virus, La Crosse virus, and the Ebola virus. The authors conclude that the nature of the risks associated with gene therapy treatments must be established and minimized as much as possible, in order to have a more positive risk/benefit ratio in favor of intervention. When all the requirements for more efficient gene delivery and safer therapeutic applications are met, gene transfer technology will become an accepted reality in the clinical setting--from the text of the article; please see the bibliography of the article) Stem Cells Volume 18, Number 1 (January 2000): 19-39. **An abstract of this article is currently available through the Web site of Stem Cells** How to find the above journals, magazines, and other publications? See Step 3: Locate of the Information Strategy for details. Questions about any or all of the above? Please let me know. |
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