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November 2001 |
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If you choose to follow any links to the abstracts and/or complete text of articles, books, and documents listed below, you will be leaving the Strategian Web site. If you wish to return to this page from the Web page you are sent to, please use the Back option of your browser. Feature Items: Morton N. Swartz Recognition and Management of Anthrax -- An Update. (... a concise, readable, and valuable review of anthrax--what it is and its effects upon the health of humans and other animals. Topics discussed include the different forms of anthrax [inhalational anthrax, cutaneous anthrax, gastrointestinal anthrax, and anthrax meningitis], symptoms, progression of the illness, chances of death, diagnosis, treatment options, etc. Other keywords and phrases -- antimicrobial drugs, B. anthracis, bacillus anthracis, bacteriology, bioterrorism, epidemiology, mortality, pathogenesis, postexposure prophylaxis, skin, terrorism, therapy, war, Zimbabwe -- please see the bibliography) The New England Journal of Medicine Volume 345, Number 22 (November 29, 2001): 1621-1626. **The complete text of the article is currently available through the Web site of The New England Journal of Medicine** Larry M. Bush, Barry H. Abrams, Anne Beall, and Caroline C. Johnson Index Case of Fatal Inhalational Anthrax Due to Bioterrorism in the United States. (... a concise but indepth description of the first case of inhalational anthrax to occur in the United States since 1978 which resulted in the death of a 63-year-old man who worked for a major tabloid newspaper based in Florida. Anthrax is a rare bacterial infection acquired by inhalation, ingestion, or cutaneous contact with the endospores of B. anthracis. The organism is normally a pathogen of large herbivorous mammals [animals that eat green plants], and infection in humans normally results from contact with infected animals or contaminated animal products, especially hides. Inhalational anthrax develops after the deposition of pathogenic endospores of B. anthracis into the alveolar spaces of the lungs. The authors state that the clinical manifestations of inhalational anthrax in this case were typical. Several days of a nonspecific prodrome [early symptoms of a disease] of fever, malaise, and myalgia were followed by a fulminant [suddenly occurring with great severity] course characterized by seizures and subsequent respiratory failure. The time from the onset of symptoms to death was six days. The authors further state that on the basis of data from experiments in primates, the dose of inhaled anthrax that is likely to be lethal in half of the humans infected is between 2500 and 55,000 endospores though studies suggest that there is wide variation in individual susceptibility to anthrax infection. Other keywords and phrases -- terrorism, war -- from the text of the article) The New England Journal of Medicine Volume 345, Number 22 (November 29, 2001): 1607-1610. **The complete text of the article is currently available through the Web site of The New England Journal of Medicine** Kevin Joseph Roche, Mary Wu Chang, and Herbert Lazarus Cutaneous Anthrax Infection. (... an image of what a cutaneous anthrax infection looks like--in this case, an infection in the arm of a seven-month-old child. Other keywords and phrases -- bioterrorism, skin, terrorism, war) The New England Journal of Medicine Volume 345, Number 22 (November 29, 2001): 1611. **The complete text of the article is currently available through the Web site of The New England Journal of Medicine** Jeanne Guillemin Anthrax: The Investigation of a Deadly Outbreak. (... an account of the investigation into the true causes of an epidemic of inhalational anthrax among humans and animals that occurred within and near Sverdlovsk, a Russian city in the foothills of the Ural Mountains. 66 people died as a result of a release of anthrax aerosol that occurred for a few hours on April 2, 1979, near a military production facility in Sverdlovsk. Other keywords and phrases -- airborne, biologic, cattle, epizootic, lymph nodes, Matthew Meselson, Rhodesia, sheep, terrorism, war, Zimbabwe -- from the text of the review [see below]) University of California Press (1999): 321 pages. **The complete text of a review of this book by James H. Steele [Volume 342, Number 18 (May 4, 2000): 1373] is currently available through the Web site of The New England Journal of Medicine** How to find the above journals, magazines, and other publications? See Step 3: Locate of the Information Strategy for details. Questions about any or all of the above? Please let me know. |
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