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Author (up) Daniolos, A.; Lerner, A.B.; Lerner, M.R. file  url
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  Title Action of Light on Frog Pigment Cells in Culture Type Journal Article
  Year 1990 Publication Pigment Cell Research Abbreviated Journal Pigment Cell Res  
  Volume 3 Issue 1 Pages 38-43  
  Keywords Solar radiation; Skin; Xenopus; Light  
  Abstract Solar radiation induces numerous biologic effects in skin but the mechanism underlying these responses is poorly understood. To study the etiology of these phenomena, we investigated the effect of light on cultured Xenopus laevis melanophores. Visible light stimulated a marked increase in intracellular cAMP levels within the first minute of irradiation. This light-induced elevation in cAMP was blocked by melatonin and was not seen in fibroblasts irradiated in a similar manner. These data show that the photoresponse of pigment cells from amphibian skin can be mediated by a cAMP-dependent mechanism and suggest that a unique member of the rhodopsin family is involved in this process.  
  Call Number Serial 2044  
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